Prothrombin (Factor II) (Last Updated - 3/29/2005)

-gets activated to form thrombin (Factor IIa) via catalysis by calcium (Factor IV), phospholipids, Factor Va & Factor Xa
-1/2-Life:
     ~50 hrs.

-click here to view an image of the clotting cascade

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References:

Goodman & Gilman's: The Pharmacologic Basis Of Therapeutics - 10th Edition - 2001. Chapter 55.